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KMID : 0390020090190030209
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Pediatric Allergy and Respiratory Disease
2009 Volume.19 No. 3 p.209 ~ p.219
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Treatment of Atopic Dermatitis : an Update and Review of the Literature
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Kim Tae-Yoon
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Abstract
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Atopic dermatitis is a chronic, relapsing, inflammatory skin disease, with genetic and environmental backgrounds. Successful management of atopic dermatitis requires a multipronged approach. Management should compromise of a disease-adapted treatment which combines adjuvant basic therapy, symptomatic relief and, if needed, anti-inflammatory treatment and the identification and avoidance of trigger factors. Topical calcineurin inhibitors are also considered to be good alternatives for the long-term control of severe atopic dermatitis. Also, new therapies such as immunomodulatory drugs, biologics, anti-IgE therapy, and CpG oligodeoxynucleotides (ODN) are considered to be effective in treatment of atopic dermatitis.
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KEYWORD
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Atopic dermatitis, Biologics, Calcineurin inhibitors, Immunomodulatory drugs
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